Wissenschaftliche Publikationen 2012

Blome, S., Aebischer, A., Lange, E., Hofmann, M., Leifer, I., Loeffen, W., Koenen, F., Beer, M.: Comparative evaluation of live marker vaccine candidates ‘‘CP7_E2alf'' and ‘‘flc11'' along with C-strain ‘‘Riems'' after oral vaccination. Veterinary Microbiology 158, 42-59, 2012.

Golde, W.T., de Los Santos, T., Robinson, L., Grubman, M.J., Sevilla, N., Summerfield, A., Charleston, B.: Evidence of activation and suppression during the early immune response to foot-and-mouth disease virus. Transboundary Emerging Disease, 584, 283-90, 2012.

Hüsser, L., Ruggli, N., Summerfield, A.: Npro of classical swine fever virus prevents type I IFN mediated priming of conventional dendritic cells for enhanced IFN-a response. Journal of Interferon Cytokine Research, 32, 221-229, 2012.

Kemter, E., Lieke, T., Kessler, B., Kurome, M., Wuensch, A., Summerfield, A., Ayares, D., Nagashima, H., Baars, W., Schwinzer, R. and Wolf, E.: Human TNF-related apoptosis-inducing ligand-expressing dendritic cells from transgenic pigs attenuate human xenogeneic T cell responses. Xenotransplantation, 19, 40-51, 2012.

Liniger, M., Summerfield, A., Ruggli, N.: MDA5 can be exploited as efficacious genetic adjuvant for DNA vaccination against lethal H5N1 influenza virus infection in chickens. PLOS ONE 7, e49952, 2012.

Liniger, M., Summerfield, A., Zimmer, G., McCullough, K.C., Ruggli, N.: Chicken cells sense influenza A virus infection through MDA5 and CARDIF signaling involving LGP2. Journal of Virology, 86, 705-717, 2012.

Liniger, M., Moulin, H.R., Sakoda, Y., Ruggli, R., Summerfield, A. Highly pathogenic avian influenza virus H5N1 controls type I IFN induction in chicken macrophage HD-11 cells: a polygenic trait that involves NS1 and the polymerase complex. Virology Journal, 9, 7, 2012.

McCullough, K.C., Bassi, I., Démoulins, T., Thomann-Harwood, L.J., Ruggli, N.:
Functional RNA delivery targeted to dendritic cells by synthetic nanoparticles. Therapeutic Delivery, 3 (9), 1077-1099, 2012.

Meyer, D., Aebischer, A., MŸller, M., Grummer, B., Greiser-Wilke, I., Moennig V., Hofmann, M.A.: New insights into the antigenic structure of the glycoprotein Erns of classical swine fever virus by epitope mapping. Virology, 433, 54-54, 2012.

Müntener, C.R., Bruckner, L., Stürer, A., Althaus, F.R., Caduff-Janosa, P.: Vigilance der Tierarzneimittel: Gemeldete unerwünschte Wirkungen im Jahr 2010. Schweizer Archiv für Tierheilkunde, 154, 57-65, 2012.

Müntener, C.R., Bruckner, L., Kupper, J., Althaus, F.R., Caduff-Janosa, P.: Vigilance der Tierarzneimittel: Gemeldete unerwünschte Wirkungen im Jahr 2011. Schweizer Archiv für Tierheilkunde, 154 (12), 513-519, 2012.

Ocaña-Macchi, M., Ricklin, M.E., Python,S., Gsell Albrecht, M., Stech, J., Stech, O., Summerfield, A.: Avian influenza A virus PB2 promotes interferon type I inducing properties of a swine strain in porcine dendritic cells. Virology 427, 1-9, 2012.

Reber, A., Kreienbrock, L., Casati, S., Chaignat, V., Schwermer, H.P.: Putative risk factors for infections with Toggenburg Orbivirus in goat herds in Southern Switzerland (Canton of Ticino). Veterinary Microbiology, 160 (1-2), 29-34, 2012.

Schorer, M., Vögtlin, A., Hilbe, M., Thür, B., Posthaus, H., Braam, P., Hadorn, D., Schwermer, H.: Überwachung des Schmallenberg-Virus in der Schweiz. Schweizer Archiv für Tierheilkunde 154, (12), 543-547.

Sharma, R., Ghasparian, A., Robinson, J.A., McCullough, K.C.: Synthetic virus-like particles target dendritic cell lipid rafts for rapid endocytosis primarily but not exclusively by macropinocytosis. PLoS One, 7(8), e43248, 2012.

Stärk, K., Griot, C.: Does the emergence of the Schmallenberg virus pose a public health risk in Europe? Disease report series for the Working Group Zoonotic Diseases, #6, 2012.

Summerfield, A.: Viewpoint: Factors involved in type I interferon responses during porcine virus infections. Veterinary Immunology and Immunopathology, 148 (1-2), 168-71, 2012.

Tamura, T., Sakoda, Y., Yoshino, F., Nomura, T., Yamamoto, N., Sato, Y., Okamatsu, M., Ruggli, N., Kida, H.: Selection of classical swine fever virus with enhanced pathogenicity reveals synergistic virulence determinants in E2 and NS4B. Journal of Virology 86, 8602-8613, 2012.

Vazquez-Calvoa, A., Saizb, J.C.; McCullough, K.C., Sobrino, F., Martin-Acebesa, M.A.: Acid-dependent viral entry. Virus Research, 167, 125-137, 2012.  

Flu away (PDF, 430 kB, 19.03.2012)(Innovation Report, April 2012)
Dr Gert Zimmer summarises his project to develop an avian influenza viruses vaccine using the innovative platform of RNA replicons to open up the possibility of large-scale immunisation of domestic poultry.